Hope through Progress: Advancing Care Globally

Sickle cell disease (SCD) is an inherited blood disorder. That means it is passed down from a parent’s genes. It causes the body to make abnormal hemoglobin. Hemoglobin is the protein in red blood cells that carries oxygen to all parts of your body. When you have SCD, your body’s tissues and organs do not get enough oxygen. Sickle cell disease is a lifelong condition. Healthy red blood cells are round and move easily all over the body. With SCD, the red blood cells are hard and sticky. They are shaped like the letter C (and like a farm tool called a sickle). These damaged red blood cells (sickle cells) clump together. Sickle Cell Traits versus Disease . People who have sickle cell trait inherited a hemoglobin S gene from only one parent. They inherited a normal gene from their other parent. People with sickle cell trait typically do not have any symptoms of sickle cell disease. However, ongoing research may show that these people may have symptoms. Importantly, they can pass on the ab...